A main Pokemon game would be good for the system. Grand Theft Auto 5 would be good too. Personally I would like to see updates of classic titles. A new Wing Commander with Mark back, or a Command and Conquer. Mabinogi or Ragnorak would make sense too. Maybe a local multiplayer version of Maple Story would be interesting. Oh and Shadowgun Legends of course...
Pikmin 4, Mortal Kombat 2 remake, Scarface: The World Is Yours remake, Waverace 64 remake, Ocaraina or time or TLO Zelda open world remake (a la botw), ZombiU remaster.