Well thermals is going to be your number 1 concern, keep it cool and look up successful OC on your GPU and get a good number to try and hit. Then start pushing her. Gradually. If she dont post after a crash or 1st time boot dont freak, just bring it back down to a safer level, stock if needed. Small OC will handle just fine, but be careful on how far you go, killing the card is the worst result and NO ONE on earth wants that.
To be clear im not a OC expert but I did just push my RX550 Up to 1403